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LSM6 Antibody, Biotin conjugated

Datasheet
Code CSB-PA013209LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LSM6 Polyclonal antibody
Uniprot No.
P62312
Target Names
LSM6
Alternative Names
LSM6U6 snRNA-associated Sm-like protein LSm6 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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LSM6 Antibodies

LSM6 Proteins

Customer Reviews and Q&A

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Target Background

Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).
Gene References into Functions
  1. LSm1-7 proteins colocalize with DCP1,DCP2 and Xrn1 in cytoplasmic foci PMID: 12515382
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
SnRNP Sm proteins family, SmF/LSm6 subfamily
Database Links

HGNC: 17017

OMIM: 607286

KEGG: hsa:11157

STRING: 9606.ENSP00000296581

UniGene: Hs.190520

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